ABOUT 'Histio Warriors' : the Documentary

‘Histio Warriors’ is a 2 hour, 25 minute feature Documentary…

Meet the “Dream Team” of Histio Doctors and specialists,

including Dr. Kenneth McClain, Dr. Carl Allen (Texas Children’s Hospital),

Dr. Lisa Filipovich, Dr. Michael Jordan (Cincinnati Children’s Hospital),

and many more…   as they discuss the latest diagnostic and treatment protocols.

Journey with Histio Families as they share their stories…

Find links and resources throughout the film for additional information,

and Learn how you can make a difference! 


The new full-length feature Documentary “Histio Warriors” is now AVAILABLE!!

Please print, fill out, and send ORDER FORM (below) with your Check payable to:


P.O. Box 4727

Glendale, CA. 91222-0727


100% of money made selling this film will go to Histiocytosis Awareness, Education and Research.

Histiocytosis is a rare blood disease which affects approximately 1 in 200,000 people, mostly children…

There are roughly 5 Diseases involved with Histiocytosis: LCH, HLH, JXG, RDD & ECD …

Those who fight these diseases are called ‘HISTIO WARRIORS’




The first ever Full-Length Feature Documentary on Histiocytosis! “Histio Warriors” is now AVAILABLE through the MOLLY RAE OF HOPE FUND, a Non-Profit 501(c)(3) Charitable Organization. The MOLLY RAE OF HOPE FUND is honored to support the Histiocytosis Research Efforts of Texas Children's Hospital and Cincinnati Children's Hospital. Thank you for your support!!!!! ***** Please visit: http://mollyraeofhopefund.mixform.com/


100% of money made selling this film will go to Histiocytosis Awareness, Education and Research.

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'Histio Warriors' opening/trailer Video Description | Download Video

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Connor~Angel Haley~Angel Nevaeh Elizabeth~Angel Megan~Angel Molly~Angel

"I really really hope and encourage everyone to share the “Histio Warriors” documentary on their page/blog (be it facebook, caring bridge, or some other source)…  It is our greatest resource for awareness right now!! Even for someone like myself whose child fought Histio, this documentary had a profound impact on me and was a great source of knowledge on the other forms of Histio I knew nothing about!  ….   So much heart and soul has gone into the making of this documentary and so many amazing courageous children have been profiled in it as well… lets show the world we are going to be heard.."

 ~ Kelly – Histio Mom of HLH Warrior, Virginia 


“We watched the video on Christmas Eve The whole thing…What an amazing job you did. You covered it all! I still cannot even fathom the amount of time, tears and love you put into this!! It is amazing. I can’t wait to give a copy to Jackie’s Oncologist. Thank you for doing this for Molly, and for all of us! It is amazing and I’m so honored to have been a part of it. …. I’m glad it was filmed when it was to show what parents go through too. I’m trying to leave that nightmare in the past and move forward with a Healthy, Amazing little girl. Thank you Melissa and congratulations on a job well done! What an accomplishment! I hope you feel as proud of yourself as I do of you!! The movie is amazing and so are you. Molly would be so proud! I’m sure she is smiling that huge smile from up above right now!!”  

~ Juliet – Histio Mom of LCH Warrior Jackie, Massachusetts 


"Melissa, I hope the whole WORLD will see it : “Histio Warriors”!!! 

I’d like to think it takes away a small little piece of the pain to know that because of Molly, you are making this documentary that will help save so so so many others in the future … you will be saving lives!"

~ Beckah – Histio Mom of LCH Warrior Elmer, Sweden


Langerhans cell histiocytosis (LCH) is the most common of the histiocytic disorders affecting both children and adults.  It can affect skin, lungs, lymph nodes, pituitary gland, spleen, liver and skeleton.  Researchers are currently trying to determine whether LCH is a type of cancer.

Diabetes insipidus (DI) is common in patients with LCH…  The result of damage to the pituitary gland affecting the kidneys.

Hemophagocytic lymphohistiocytosis (HLH) is often referred to as either “primary” which is hereditary (FHL/FHLH), or “secondary” associated with infections, viruses, autoimmune diseases, and malignancies/cancers.  Considered the most aggressive and potentially fatal of the Histiocytic Disorders, resulting from inappropriate pro longed activation of lymphocytes and macrophages.  HLH can attack the central nervous system and EVERY organ in the body.

Macrophage Activation Syndrome (MAS) is a severe life-threatening, complication of several chronic Rheumatic diseases of childhood.  It is closely related and pathophysiologically similar to reactive (secondary) HLH.

Juvenile xanthogranuloma (JXG) involves the over-production of a histiocyte called dendritic cell.  Characterized by histiocytic lesions which can infiltrate the skin, soft tissue, internal organs and immune system.  80-90% of patients are children less than two years old.

Rosai-Dorfman disease (RDD) involves the over-production of a type of white blood cell called non-Langerhans sinus histiocyte.  These cells accumulate, most often in the lymph nodes, but it can also lead to organ damage.  It is most commonly seen in the first 10 years of life, but it also occurs in adult patients.

Erdheim-Chester disease (ECD) is a non-Langerhans cell histiocytosis that most often becomes apparent in middle age.  This disease mostly affects long bones, but can also affect the eyes, kidneys, skin, brain, lung, heart, pituitary gland, and the posterior abdominal wall.

“The Story of Sacrifice, Love, and the Fight to save others”





On May 24th, 2011, my 14 year-old cousin Molly Rae passed away from a very rare disease called Histiocytosis.  Molly developed a type of Histiocytosis called Hemophagocytic Lymphohistiocytosis, also known as HLH. 

Healthy her whole life, Molly passed away only 6 weeks from her diagnosis, and was buried on her 15th Birthday.  This disease attacked EVERY organ in her little body, including her Central Nervous System causing her to also lose her sight.  Molly began Chemotherapy, and needed a Bone Marrow Transplant….

HLH is described as “worse than Cancer”, and Histiocytosis is considered an "Orphan Disease”, receiving little to no Federal Funding. 

How can it be that children are dying from something that few people, including your doctors, know about? 

Histiocytosis is caused by the over-production of a white blood cell called the Histiocyte.   We all have Histiocytes in our bodies, they are part of our immune system.  When we get sick, with a virus or infection, these Histiocytes come out and attack the bad things affecting us, and when their job is done they settle back down..   With Histiocytosis, those same cells come out, but cant differentiate the good from the bad and begin to attack anything or everything they can, and they don’t stop…

It can happen to anyone at any time, any race, gender or age.  It doesn’t discriminate.

There are roughly 5 diseases under the umbrella of Histiocytosis, HLH is just one of these life-threatening diseases, and it can begin as simply as a fever or a rash.

Histiocytosis Awareness is an urgent need, as many children are often diagnosed too late.

I began the first ever Full-Length Feature Documentary Film on Histiocytosis, called "Histio Warriors”…   Since Molly’s death, 10 more children in my film have died from this so-called “rare disease”. 

This important Documentary examines the group of Histiocytic Diseases, and includes interviews with the ‘Dream Team’ of Doctors, Scientists, and Specialists from around the Country, as well as various Family stories throughout their journey to find understanding and promote education, both to the General Public and the Medical Community. The film also includes many National & International Resources to aid those in their fight with this disease.

“I know that Molly has been by my side in some way throughout this journey to find understanding, and support awareness and education for these diseases.. and if more children can be saved through Molly’s spirit and experience, I know she would want that…  I know it cannot bring back those we’ve lost, but it can be the start of helping others to live.”

100% of all money made selling this film goes to Histiocytosis Research and Education through my new Non-Profit Organization: The “Molly Rae of Hope Fund”.

A graduate of New York University’s Tisch School of the Arts, I have worked in the Entertainment industry for over 20 years, in a variety of different areas (producing, directing, acting, editing).

“Histio Warriors” is my first Full-Length Feature Documentary, and was a 2012 Buffalo International Film Festival Selection!   Inspired by, and for, my dear cousin Molly, and dedicated to ALL the Histio Warriors, Angels, and Families who have been affected by this horrible Disease.

Thank you for your support, and please continue to fight for Awareness!

~ Melissa L. Berger

President, Molly Rae of Hope Fund

Director/Producer:  “Histio Warriors”: The Documentary





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MOLLY RAE OF HOPE FUND ~ Fundraising for Histio Research!

MOLLY RAE OF HOPE FUND is a non-profit 501c3 100% charitable organization for Histiocytosis Research and Education ... Check out our page of Fundraisers! COPY AND PASTE THIS LINK : www.mollyraeofhopefund.mixform.com


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